Among 271 fetuses exposed to chemotherapeutic agents during the first trimester, 19. The basics what is chemotherapy and how does it work. Terminology used in describing chemotherapy chemotherapy is administered with a variety of treatment schedules designed according to the intent and responsiveness of therapy. Containers that held hazardous waste chemotherapy drugs, and do not meet the definition of empty, are hazardous waste when discarded. Chemotherapeutic agents definitions flashcards quizlet. Chapter 10 antibiotics and chemotherapeutic agents. These drugs are very different in their chemical composition, how they are taken, their usefulness in treating specific forms of cancer, and their side effects. Chapter 12 chemotherapeutic agents flashcards quizlet. Chemotherapy is a type of cancer treatment that uses one or more anticancer drugs chemotherapeutic agents as part of a standardized chemotherapy. Learn vocabulary, terms, and more with flashcards, games, and other study tools. It uses special drugs to kill cancer cells in the body.
This is a list of chemotherapeutic agents, also known as cytotoxic agents, that are known to be of use in chemotherapy for cancer. By contrast, an antibiotic is a product of the metabolism of a microorganism. Tumors are made up of cells that are reproducing at abnormally high rates. Ongoing treatment strategies include combining chemotherapy with targeted molecular therapeutic agents, antiangiogenic treatments, and biologicals. Most chemotherapeutic agents can cause varying degrees of local tissue injuries when extravasated. This teacherdeveloped 5th grade word list covers all the basics to prepare students for middle school. General characteristics of chemotherapeutic agents 3. Chemotherapeutic agents, also referred to as antineoplastic agents, are used to directly or indirectly inhibit the proliferation of rapidly growing cells, typically in the context of malignancy. Antimicrobial, antiparasitic, and antineoplastic chemotherapeutic agents are distinguished. Sep, 2017 the adverse health effects associated with antineoplastic agents cancer chemotherapy drugs, cytotoxic drugs in cancer patients and some noncancer patients treated with these drugs are well documented. Pdf antibiotics and chemotherapeutic agents researchgate. Both the size and distribution of charge of the sulfonamides and paba molecule are very similar, so sulfa drug play a role of metabolism antagonist. Classification of chemotherapeutic agents based on their differential in vitro effects on dendritic cells article pdf available in cancer research 6917. Medication errors in administration of chemotherapeutic.
Cancer chemotherapeutic agents are often given in combination because cellular interactions such as inhibiting cell replication and promoting apoptosis among the drugs cause more cancer cell death. Anthracyclines are very efficient chemotherapeutic agents, derivatives of streptomyces peucetius which is a pigment producing bacteria. An agent used to treat cancer administered in regimens of one or more cycles, combining two or more agents over a period of days to weeks. Chemotherapy agent an overview sciencedirect topics. Note that the microbiologists definition of a chemotherapeutic agent requires that the. Chemotherapeutic agents, also referred to as antineoplastic agents, are used to directly or indirectly inhibit the proliferation of rapidly growing. Classification of chemotherapeutic agents based on their differential. Full text full text is available as a scanned copy of the original print version. Once again, we employed the same dual criteria to define a. Medication errors in administration of chemotherapeutic agents. Chemotherapeutic agent synonyms, chemotherapeutic agent pronunciation, chemotherapeutic agent translation, english dictionary definition of chemotherapeutic agent. Information and translations of nonchemotherapeutic in the most comprehensive dictionary definitions resource on the web. They are classified according to their mechanism of action and include alkylating agents, antimetabolites, topoisomerase inhibitors, and mitotic inhibitors. This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision.
Therefore, payment may be made for an fda approved drug or biological or cancer chemotherapeutic agent if. Microbial pathogens grow on and within the body of other living beings and their colonization may lead to disease, disability, and death. Information and translations of chemotherapeutic agent in the most comprehensive dictionary definitions resource on the web. Chemotherapy often abbreviated to chemo and sometimes ctx or ctx is a type of cancer treatment that uses one or more anticancer drugs chemotherapeutic agents as part of a standardized chemotherapy regimen.
Chapter 3 principles of chemotherapy ray page, do, phd, and chris takimoto, md, phd the effective use of cancer chemotherapy requires an understanding of the principles of tumor biology, cellular kinetics, pharmacology, and drug resistance. The local delivery of controlled release antimicrobials provides a means of professionally administering chemotherapeutic agents directly into the periodontal pocket in order to provide slow release of the drug. As a generator of hazardous waste, you must comply with the applicable requirements in shs. Chemotherapeutic agents and their applications balaji college of pharmacy mr. Chemotherapy may be given with a curative intent which almost always involves combinations of drugs, or it may aim to prolong life or to reduce symptoms palliative chemotherapy. Chemotherapy may be given with a curative intent which almost always involves combinations of drugs, or it may aim to prolong life.
Chemotherapeutics definition of chemotherapeutics by. Chemotherapeutic definition of chemotherapeutic by the free. Local coverage article for approved drugs and biologicals. Pdf the ideal antimicrobial agent should he nontoxic to the host selective toxicity, nonallergenic, soluble in body fluids, able to be maintained. Chemotherapeutic agent definition of chemotherapeutic. Classification of anticancer drugs based on their differential impacts on dcs.
Definition of nonchemotherapeutic in the definitions. Antihypertensive drugs are often given in combination because some of the side effects. Chemotherapeutic agents definitions learn with flashcards, games, and more for free. Each drug is listed once at present, though it might fall in more than one subsection. Pdf despite the crucial roles dendritic cells dc play in host immunity against. Since chemotherapeutic drugs cannot distinguish between normal cells and cancer cells, both types of cells are affected by chemotherapy. However, the value of chemotherapy lies in the fact that the killing effect of chemotherapeutic agents has a. Definition of chemotherapy nci dictionary of cancer. New chemotherapeutic agents with more specificity, less toxicity, and the improved ability to halt molecular pathways of tumorigenesis are being developed and need to be optimized. The medical treatment of extravasation is based on proper maintenance of the intravenous iv line and application of cold or warm compresses, plus the use of antidotes when available. Chemotherapy may be given by mouth, injection, or infusion, or on the skin, depending on the type and stage of the cancer being treated. Definition of chemotherapeutic agent in the definitions.
With the direct placement of the drug in the periodontal pocket, the chance of drug resistance is. It is usually used to refer to antineoplastic drugs. Chemotherapeutics definition of chemotherapeutics at. The very nature of antineoplastic agents make them harmful to healthy cells and tissues as well as the cancerous cells. Chemotherapeutic agents knowledge for medical students and. Chemotherapeutic agent legal definition of chemotherapeutic agent. Control of microbial growth online textbook of bacteriology. Chapter 9 chemotherapeutic agents 02 authorstream presentation.
The treatment of cancer using specific chemical agents or drugs that are selectively destructive to malignant cells and tissues. Chemotherapeutic agents list of high impact articles ppts. Nov, 2014 chemotherapeutic agents and their applications. Chemotherapeutic definition is of, relating to, or used in chemotherapy. Toxicity of chemotherapeutic agents to normal cells is the cause of unpleasant side effects. Drugs or biologicals and cancer chemotherapeutic agents approved for marketing by the food and drug administration fda are considered safe and effective for purposes of this requirement when used for indications specified on the labeling. Chemotherapeutic agents should be handled according to the a. More than 100 chemotherapy or chemo drugs are used to treat cancer either alone or in combination with other drugs or treatments. Still, significant challenges remain for specific cancer types, such as glioblastoma, in which a combination of early detection, surgery, chemotherapy, and radiotherapy cannot extend survival beyond 12 years. Here we report differential impacts of 54 anticancer drugs on dc. The term generally implies a chemical that has been synthesized by chemists or produced by a modification of a preexisting chemical. Pdf classification of chemotherapeutic agents based on. Chemotherapeutic agents are also known as cytotoxic agents. Chemotherapy definition of chemotherapy by merriamwebster.
Such agents are toxic to cells with high proliferative ratese. Drugs with different patterns of resistance should be combined to minimize crossresistance. Thanks to the development of new, effective chemotherapeutic agents. Some are cytotoxic, meaning that the drugs damage the cells and prevent them from replicating or increasing in number. In order to understand how these medications work, we need to understand a bit about tumor cells. Chemotherapeutic article about chemotherapeutic by the free. Chemotherapeutic agents include substances of natural origin for example, antibiotics and synthetic preparations for example, sulfanilamides, nitrofurans, and paraaminosalicylic acid. Other articles where chemotherapeutic agent is discussed. Nov 22, 2012 cancer is a disease in which there is uncontrolled multiplication and spread within the body of abnormal forms of bodys own cells. Chemotherapeutic agents knowledge for medical students. Sep 28, 2019 chemotherapeutic plural chemotherapeutics medicine, oncology a chemical agent used in chemotherapy 2005, michael g. Chemotherapeutic agents stateautocollapse shows the template collapsed to the title bar if there is a navbar, a sidebar, or some other table on the page with the collapsible attribute.
Hazardous waste has specific management requirements for marking, labeling, time limits for storing, transportation, disposal methods and recordkeeping. Pdf classification of chemotherapeutic agents based on their. Chemotherapeutic agent definition of chemotherapeutic agent. Several novel chemotherapeutics that target specific signaling pathways are now. The ideal antimicrobial agent should he nontoxic to. Chemotherapy definition is the therapeutic use of chemical agents to treat disease. Chemotherapeutic agents and their applications authorstream. How chemotherapy drugs work american cancer society.
Get a printable copy pdf file of the complete article 1. The treatment of a disease with a chemical substance is called chemotherapy and the chemical substance used for the purpose is known as a chemotherapeutic. Chemotherapeutic definition of chemotherapeutic by merriam. Some types of cancer can be treated with just chemotherapy. Chemotherapeutic agents stateexpanded to show the template expanded, i. Chemotherapy is used to describe medications that treat cancer.
Chemotherapeutic agent article about chemotherapeutic agent. The development of these agents began in the 1940s. Predisposing factors for laryngeal candidiasis include immunodeficiency syndromes, immunosuppressive medications e. They are classified according to their mechanism of action and include alkylating agents, antimetabolites, topoisomerase inhibitors, and mitotic. It includes alkylating agents, antimetabolites, antitumor antibiotics, anthracyclines, topoisomerase inhibitors, etc.1366 1104 909 219 494 1363 402 1212 566 92 861 905 45 1063 1326 1203 879 700 798 260 477 449 1482 560 1255 1107 86 1021 628 132